منابع مشابه
P16: The Effect of PTSD on Memory
Post-traumatic stress disorder (PTSD), panic disorder and phobia manifest in ways that are consistent with an uncontrollable state of fear. Impaired memory for elements of the traumatic experience is a core feature of PTSD, and clinical complaints of memory impairment for non-trauma-related stimuli are common. Several studies have documented generalized memory impairment among patients with com...
متن کاملP16 expression in odontogenic tumors.
AIMS AND BACKGROUND The aim of the study was to examine the immunohistochemical expression of a cell-cycle-related factor (p16) in order to elucidate its role in the growth and diffusion of odontogenic tumors. STUDY DESIGN Thirty-six odontogenic tumors were divided into two groups according to their clinical behavior: group A and group B composed of tumors at low and high risk of recurrences,...
متن کاملp16 in HPV-associated cancers
Infections with high-risk human papillomaviruses (HPV) account for approximately 5% of all human cancers. Cervical cancer, in particular, is almost universally caused by “high-risk” HPV infections and these HPVs also cause a large fraction of other anogenital tract cancers as well as oral carcinomas. The viral E6 and E7 proteins are the universal oncogenic drivers of HPV-associated cancers, and...
متن کاملCoordinated transcription of ANRIL and P16 genes is silenced by P16 DNA methylation.
Objective To investigate the relationship between the transcription of ANRIL, P15, P14 and P16 at the same locus and the regulation mechanism of ANRIL. Methods Publicly available database of Cancer Cell Line Encyclopedia (CCLE) was used in bioinformatic analyses. Methylation of CpG islands was detected by denaturing high performance liquid chromatography (DHPLC). Gene transcript levels were d...
متن کاملExpression and characterization of Syrian golden hamster p16, a homologue of human tumor suppressor p16 INK4A.
The p16(INK4A)/CDKN2A tumor suppressor gene is known to be inactivated in up to 98% of human pancreatic cancer specimens and represents a potential target for novel therapeutic intervention. Chemically induced pancreatic tumors in Syrian golden hamsters have been demonstrated to share many morphologic and biological similarities with human pancreatic tumors and this model may be appropriate for...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 2018
ISSN: 0021-9746,1472-4146
DOI: 10.1136/jclinpath-2018-205216